Aphrodisias is about 2 hours away from Ephesus and 2,5 hours from Pamukkale. It can be visited by rental car or private tours arranged by local travel agencies.
Thereâ€™s also a possibility to visit by public transportation but a bit complicated and time consuming especially if you have limited time.
If you prefer to rent a car, you arrive in Nazilli or Tavas first and then take the road D585. It is 95km to Aydin, 110km to Denizli, 130km to Pamukkale, 130km to Ephesus, 140km to Kusadasi and 220km to Izmir.